Multiple vehicles were involved in wrecks reported on both sides of Interstate 75 between the Shallowford Road and Bonny Oaks Drive exits.
The crashes happened around 5:10 p.m. Friday.
It was reported that one vehicle rolled over and there may have been victims ejected on both the northbound and southbound lanes.
Some lanes were blocked in both directions.
It was expected to take about an hour to get them cleared.