McCallie got on the board first, but wound up losing 28-6 in high school football playoff action on Friday night.
Deangelo Hardy scored on a six-yard run in the second quarter.
However, Mike Archie then fired 10-yard and 34-yard strikes to put Brentwood up 14-6 at the half.
Brentwood added scores on runs in the third quarter and the fourth quarter.