Vanderbilt stunned #6 Tennessee, 66-65, on Wednesday night in Nashville as Tyrin Lawrence hit a three-pointer from the corner.
Students stormed the court at Memorial Gymnasium to celebrate the Commodores' first victory over a Top 10 team since 2016.
The Vols held a 34-32 lead at the half, but Vanderbilt took a three-point lead on an Ezra Manjon layup. The Vols regained the lead, 40-39, on a Toby Awaka dunk.
Tennessee led by as many as five points, but Vanderbilt went back in front, 49-48, on a Jordan Wright layup.
It was tied, 60-60, with just over four minutes left after a Santiago Vescovi layup. A Vescovi three knotted it at 63 with just over two minutes on the clock.
A jumper by Olivier Nkamhoua put the Vols up 65-63 with 52 seconds remaining.
A Vescovi miss at the foul line with eight seconds left gave Vanderbilt their chance.
Vescovi scored 14 points, while Nkamhoua and Julian Phillips had 10 each.