Olivier Nkamhoua had a huge second half to lead the Tennessee Vols past Duke, 65-52, and a berth in the Sweet 16.
Nkamhoua contributed 27 points as Tennessee led much of the game and pushed the advantage to double digits in the late minutes.
Santiago Vescovi was another Vol hero with his swarming defense and 14 points.
Tennessee will await the winner of Florida Atlantic and Fairleigh Dickinson, a 16 seed that shocked 1 seed Perdue.
The Vols had closed out the first half with a 14-2 run to lead 27-21.
Nkamhoua started the scoring with a layup at the 18:36 mark, then the Blue Devils scored twice for a 6-2 lead.
A Josiah-Jordan James jumper got the Vols back ahead at 11-10, and a pretty Julian Phillips dunk on a toss from Vescovi made it 13-10.
Duke went on their own run to go in front 19-13 before Vescovi connected with a three-pointer and then he had two foul shots to pull within a point.
A Jonas Aidoo dunk put Tennessee ahead 22-21, then Tyreke Key connected on a three-pointer from the left side. Aidoo hit a layout with a second left in the half to send Tennessee to intermission up by six points.